SAKAJ Mirena

Sito web (scheda personale)
Dipartimento di Scienze Molecolari e Nanosistemi
Sito web struttura:
Sede: Campus scientifico via Torino (edificio Alfa)

1. Education

09/2018 – in progress—PhD student in Science and Technology of Bio and Nanomaterials, under the supervision of Prof. Riello.

02/2016 – 03/2017 – Second level post graduated Master course in Drug Design and Development (DDD) at the University of Pavia, Italy. Topics related to the following areas: Drug Design, Advanced Organic Synthesis, Drug Discovery from Medicinal Plants, New Methods of Synthesis in Medicinal Chemistry Chiral Compounds in Medicinal Chemistry, Biocatalysis and Drug Development and Advanced Medicinal Chemistry, Patentability of Drug candidates, Preclinical development of Drugs, Clinical monitoring.

2014 – Qualification for practicing the profession of Pharmacist at the University of Bari, Italy.

2013 – Master’s degree in Pharmacy and Industrial Pharmacy with a theoretical thesis entitled “New targets for the development of anti- HCV therapies” under the supervision of Prof. Dr. Saverio Cellamare at the University of Bari, Italy.

2006 – High school diploma specialising in the science subjects – Albania.

2. Work experience

05/2017 – 08/2018 – Early stage researcher, at the Department of Physics-Chemistry, University of Pavia, Italy. Tasks performed: physical-chemical characterisation of solids of pharmaceutical interest. The research activity focuses mainly on the resolution of problems related to the pre-formulation of drugs: crystalline polymorphism, amorphous content quantification, drug-excipient compatibility, salt and co-crystalline preparation to improve pharmaceutical drug behaviour, using spectroscopic and thermal techniques.

09/2016 – 03/2017 –  Erasmus Internship under the supervision of Prof. Dr. Jörg Rademann and Dr. Arkona at Freie Universität Berlin, Institut für Pharmazie, Germany. Tasks performed: application of fragment based screening to detect inhibitors of human USP, performing of biochemical/cellular assays for the inhibitor evaluation. Cell cultures techniques, delivery of the peptides into human tumor cells, fluorescence live cell imaging, cell viability testing. Electroporation. Chemical synthesis of the inhibitors and solid phase peptide synthesis. Basic biochemical techniques: recombinant protein expression in E.Coli, protein purification, chemical derivation of proteins, enzyme assays and immunoblotting.

2014 – 2015 – Pharmacist at “Al Duomo Pharmacy”, Chioggia – Venice, Italy. Tasks performed: galenic preparation of medicines, dispensation of SOP, OTC and drugs with obligatory prescription and organisation of the pharmacy.

3. Training experience

07/11/2018 - 15/11/2018 - Training in Peptide Synthesis under the supervision of Prof. Christian Heinis, at Ecole Polytechnique federale de Lausanne, Switzerland.

27/02/2018 – Professional training course of DSC and modulated DSC (differential scanning calorimetry) with Dr. Marco Coletti, at TA Instruments – Divisione di Waters SpA Viale T. A. Edison 110, 20099 Sesto San Giovanni (MI).

28/02/2018 - Professional training course of TGA (thermal gravimetric analysis) with Dr. Marco Coletti, at TA Instruments – Divisione di Waters SpA Viale T. A. Edison 110, 20099 Sesto San Giovanni (MI).

8/04/2016 – Workshop on “Structural analysis of PROTEIN-LIGAND complexes. Prediction of ADME properties” with Dr. Johannes Kirchmair (University of Hamburg) and Dr. Stefania Monteleone (Leopold-Franzen-University Innsbruck) at the University of Pavia, Italy.

09/2011 – 03/2012 – Internship at “Pharmacy Scarola”, Palo del Colle – Bari, Italy.

4. Foreign languages

Albanian: mother tongue. Italian: C2 written and spoken. English: C1 written and spoken. German: A2 written and spoken.