Marco Salvatore NOBILE

Position
Associate Professor
Roles
Delegate for Digital Innovation and Integrity in Research
Telephone
041 234 8417
E-mail
marco.nobile@unive.it
Academic discipline
Informatics [INFO-01/A]
Website
https://www.unive.it/web/en/19197/people/marco.nobile(personal record)
Office
Department of Environmental Sciences, Informatics and Statistics
Website: https://www.unive.it/dep.dais
Where: Campus scientifico via Torino
Room: office 514 (Alfa building, 5th floor)
Research Institute
Research Institute for Complexity

Teaching activity current year

Teaching activity previous years

HOSPITALITY INNOVATION AND E-TOURISM [CT9]
Laurea

DIGITAL MANAGEMENT [ET7]
Laurea

Activities and research skills

Academic discipline
Informatica [INFO-01/A]
Settore Scientifico Disciplinare (SSD) affine
SISTEMI DI ELABORAZIONE DELLE INFORMAZIONI [ING-INF/05]
Geographic areas in which the research experience mainly applies
Internazionale: Europa, Estremo Oriente, America Settentrionale, Africa Caraibi e Pacifico
Known languages
Italiano (scritto: madrelingua parlato: madrelingua)
Inglese (scritto: avanzato parlato: avanzato)
Participation in editorial boards of scientific journals/book series
Associate Editor per IEEE Transactions on Artificial Intelligence
Associate Editor per Frontiers in Genetics, section Computational Genomics
Guest Editor per IEEE Computational Intelligence Magazine e BMC BIoinformatics
Participation as referees of national and international research projects
Austrian Academy of Sciences / Österreichische Akademie der Wissenschaften. Review of a project submitted to the call “Digital Humanities: New Potentials through Artificial Intelligence in the Humanities, Cultural Studies and Social Sciences”.

Reviewer for the European project "EUTOPIA_HEALTH", Seed Funding Call.
Main departmental research areas and fields
Area: Biomedicina Linea: Diagnosi
Area: Biomedicina Linea: Terapia
Area: Informatica Linea: ARTIFICIAL INTELLIGENCE
Area: Informatica Linea: BIOINFORMATICS
Area: Informatica Linea: DISTRIBUTED SYSTEMS
Area: Informatica Linea: INFORMATION SYSTEMS
Artificial Intelligence for biology and medicine
Keywords:
Computer science, Biological sciences
High-Performance Computing
Keywords:
Computer science, Parallel computing
Computational Intelligence
Description:
Global optimization meta-heuristics (evolutionary, swarm intelligence); uncertain reasoning and fuzzy logic
Keywords:
Computer science
Computational drug discovery
Other members of the research group:
Alessandro ANGELINI
Leone BACCIU
Achille GIACOMETTI
Matteo GRAZIOSO
Silvia MULTARI
Interpretable AI for clinical decision support
SSD:
INF/01
Modeling, simulation and analysis of complex systems in astrophysics
SSD:
INF/01
Other members of the research group:
Leone BACCIU
Matteo GRAZIOSO
Sabina ROSSI
A novel integrated cyclic peptide-based platform for precision delivery of nucleic acid-based therapeutics (ALLIANCE)
Funding body:
National Center for Gene Therapy and Drugs based on RNA - Piano Nazionale di Ripresa e Resilienza (PNRR) - Ministero dell'università e della ricerca e Unione Europea (NextGenerationEU)
Type:
Altri programmi ministeriali
Role in the project:
LD
Starting date:
Year: 2024 Length in months: 12
Other members of the research group:
Alessandro ANGELINI
Fabrizio FABRIS
Giulia FIORANI
Cristian FREGONESE
Achille GIACOMETTI
Sara LINCIANO
Sara LINCIANO
Silvia MULTARI
Federico POLO
Flavio ROMANO
Zhanna ROMANYUK
Matilde SALVADORETTI
Alessandro SCARSO
Marta SIMEONI
CONVECS – COmuNità VEneta per il Calcolo Scientifico
Funding body:
Programma PR Veneto FESR 2021-2027, Priorità 1 - Obiettivo specifico 1.1 - Azione 1.1.2.
Type:
Altri finanziamenti per progetti di ricerca
Role in the project:
PT
Sito di progetto:
https://convecs.it/
Starting date:
Year: 2024 Length in months: 36
Stochastic Differential Equations on GPU for Optimization (SDEGnO)
Funding body:
Bando a Cascata del Centro Nazionale ICSC – “National Centre for HPC, Big Data and Quantum Computing” – codice CN00000013, Spoke 3 – “Astrophysics and Cosmos Observation” a valere sui fondi PNRR assegnati al Programma HPC finanziato sui fondi PNRR MUR
Type:
Altri programmi ministeriali
Role in the project:
LD
Sito di progetto:
https://www.msnobile.eu/index.php/sdegno-stochastic-differential-equations-on-gpus-for-optimization/
Starting date:
Year: 2024 Length in months: 12
Other members of the research group:
Sabina ROSSI

Publication highlights

Capitoli, Giulia; Nobile, Marco S.; Ambags, Emma L.; L'Imperio, Vincenzo; Provenzano, Michele; Liò, Pietro Assisting clinical diagnosis with interpretable fuzzy probabilistic modelling in BMC MEDICAL INFORMATICS AND DECISION MAKING, vol. 25 (ISSN 1472-6947)
DOI 2025, Journal Article - ARCA card: 10278/5103559


Gallese, Chiara; Scantamburlo, Teresa; Manzoni, Luca; Giannerini, Simone; Nobile, Marco S. FanFAIR: sensitive data sets semi-automatic fairness assessment in BMC MEDICAL INFORMATICS AND DECISION MAKING, vol. 25 (ISSN 1472-6947)
DOI 2025, Journal Article - ARCA card: 10278/5103560


Lotti, Fiorenza; Melixetian, Marine; Vlachou, Thalia; Nobile, Marco S; Bacciu, Leone; Malferrari, Marco; Quaresima, Nicolò; Rapino, Stefania; Marocchi, Federica; Barberis, Massimo; Soriani, Chiara; Gallo, Barbara; Mollo, Velia; Ferrarotto, Ilaria; Bossi, Daniela; Ferrucci, Pier Francesco; Pelicci, Pier Giuseppe; Luzi, Lucilla; Lanfrancone, Luisa GPNMB marks a quiescent cell population in melanoma and promotes metastasis formation in EMBO REPORTS, vol. 26, pp. 3804-3830 (ISSN 1469-3178)
DOI 2025, Journal Article - ARCA card: 10278/5102008


Bacciu, Leone; Urso, Mario; Coelho, Vasco; Cazzaniga, Giorgio; Pincelli, Angela Ida; Garancini, Mattia; Papetti, Daniele M.; Besozzi, Daniela; Capitoli, Giulia; Galimberti, Stefania; Vargiolu, Alessia; Fusco, Nicola; Gianatti, Andrea; Pagni, Fabio; L'Imperio, Vincenzo; Nobile, Marco S. MiThyCA: A Computational Pathology Pipeline for the Identification of Microscopic Foci of Papillary Thyroid Carcinoma-Like Nuclear Features with AI in Whole-Slide Histological Images in ENDOCRINE PATHOLOGY, vol. 36, pp. 34 (ISSN 1046-3976)
DOI 2025, Journal Article - ARCA card: 10278/5104709


Lupi, Amalia; Nobile, Marco Salvatore; Bianco, Roberto; Gerosa, Gino; Quaia, Emilio; Pepe, Alessia Strain analysis in mitral regurgitation using interpretable machine learning in JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, vol. 27 (ISSN 1097-6647)
DOI 2025, Abstract in Rivista - ARCA card: 10278/5095390


List of publications

Curriculum vitae

Marco S. Nobile received the PhD in Computer Science from the University of Milano-Bicocca (Italy) in 2015. He then spent 4 years as post-doc researcher at UNIMIB, before moving to the Eindhoven University of Technology (Eindhoven, The Netherlands) as Assistant Professor in 2019. He then moved as Associate Professor to the Department of Environmental Sciences, Informatics and Statistics of the Ca' Foscari University of Venice (Italy) in 2021. 

During his career, he has been visiting student and researcher in several institutions, notably the University of Tokyo (Japan), the Research Center for Advanced Science and Technology (RCAST, Tokyo, Japan), the North Carolina State University (NC, USA), and the Vanderbilt University (TN, USA).

At the Ca' Foscari University he is serving as Rector's delegate for Digital Innovation for Research. He is also member  of the Joint Teaching Staff-Student Committee, representing the Bachelor's Degree in "Hospitality Innovation". 

Marco S. Nobile is currently member of the Bicocca Bioinformatics, Biostatistics and Bioimaging (B4) research center (Monza, Italy). He is senior member of the IEEE and co-chair of the Bioinformatics and Bioengineering Technical Committee (IEEE BBTC). From 2019 to 2024 he has been chair of the IEEE CIS Task Force on advanced representation in biological and medical search and optimization. He is member of the COST Action CA21169 “Information, Coding, and Biological Function: the Dynamics of Life (DYNALIFE)”, where he belongs to the Working Group “Statistical and probabilistic modelling and analysis, bioinformatics and machine learning”. Since 2025 he is also vice-coordinator of the CONVECS project ("Comunità Veneta per il Calcolo Scientifico). 

His main research interest is Computational Intelligence (i.e., bio-inspired algorithms, neural networks, evolutionary computation, swarm intelligence, and fuzzy reasoning) applied to complex problems in biomedicine. He also works on the development of interpretable / trustable AI methods for clinical decision support, and investigates the ethical aspects of AI in medicine. He worked extensively on medical image analysis (supervised and unsupervised) and proteomics. He has a long experience with modeling and simulation of complex systems, either deterministic, stochastic, and hybrid. He investigates the emergent phenomena in nature, bird flocks in particular, using Computational Intelligence and Big Data. Marco S. Nobile worked on high-performance computing (GPUs in particular), leveraging HPC infrastructures both in Europe (e.g., CINECA in Italy and surfSARA in the Netherlands) and the United States (at ORNL and at Vanderbilt). 

Marco S. Nobile was the recipient of the best paper award at the 2019 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (IEEE CIBCB 2019) and the 2022 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (IEEE CIBCB 2022). He also won the best abstract award at the 83th Congress of the Italian Cardiology Society (SIC). In January 2024, he was the recipient of the "Shark Tank award" at CMR2024, the Global Conference on Cardiac Magnetic Resonance. 

He is currently Associate Editor of the scientific journals IEEE Transactions on Artificial Intelligence (IEEE TAI). In the past, he served as editor for  Frontiers in Genetics (specialty Computational Genomics). He also served as guest editor for a special issue on IEEE Computational Intelligence Magazine and BMC Bioinformatics. 

As of October 2023, Marco S. Nobile published more than 100 peer-reviewed manuscripts and mentored seven doctoral students. He patented a method for patient-optimal inversion time in cardiac magnetic resonance exams, extended with a PCT international application.