Alessandro ANGELINI

Position
Associate Professor
Telephone
041 234 8944 / 041 234 8590 / 041 234 8600 / 041 234 8604
E-mail
alessandro.angelini@unive.it
Academic discipline
Biochemistry [BIOS-07/A]
Website
www.unive.it/people/alessandro.angelini (personal record)
Office
Department of Molecular Sciences and Nanosystems
Website: https://www.unive.it/dep.dsmn
Where: Campus scientifico via Torino
Room: room 613 (ALFA building, 6th floor) / research lab 1 (BETA building, 3rd floor)
Office
European Center for Living Technology (ECLT)
Where: Ca' Bottacin
Research Institute
Research Institute for Complexity
Safety Role
Preposto di Laboratorio
Responsabile dell’Attività di Didattica e Ricerca in Laboratorio (RDRL)

Activities and research skills

Academic discipline
Biochimica [BIOS-07/A]
Settore Scientifico Disciplinare (SSD) affine
Chimica farmaceutica [CHEM-07/A]
Geographic areas in which the research experience mainly applies
Internazionale: Europa, America Settentrionale
Known languages
Italiano (scritto: madrelingua parlato: madrelingua)
Inglese (scritto: avanzato parlato: avanzato)
Participation in editorial boards of scientific journals/book series
2022 – present: Associate editor for Molecular Recognition – Frontiers Molecular Biosciences
2024 – present: Associate editor for Molecular Diagnostics and Therapeutics – Frontiers Molecular Biosciences
Participation as referees of national and international research projects
1. Referee for research grant application proposals to the Dutch Research Council (NOW – Netherlands)
2. Referee for research grant application proposals to the Auckland Medical Research Foundation (AMRF – New Zealand)
3. Referee for research grant application proposals to the EUTOPIA Alliance (European Union)
4. Referee for research grant application proposals to the Swiss National Science Foundation (SNSF – Switzerland)
5. Referee for research grant application proposals to the French National Research Agency (ANR – France)
6. Referee for research grant application proposals to the Experientia Foundation (Czech Republic)
7. Referee for research grant application proposals to the Israel Science Foundation (ISF – Israel)
Main departmental research areas and fields
Area: Biomedicina Linea: Diagnosi
Area: Biomedicina Linea: Terapia
Area: Chimica Fisica e Materiali Linea: Sintesi Organica
Area: Informatica Linea: ARTIFICIAL INTELLIGENCE
Area: Informatica Linea: BIOINFORMATICS
Evoluzione molecolare di peptidi e proteine
Description:
Molecular evolution of peptides and proteins
Keywords:
Applied biology, Molecular evolution, Structural biology
ATECO code:
[72.11] - ricerca e sviluppo sperimentale nel campo delle biotecnologie
Sviluppo di nuove tecnologie per evoluzione diretta di biomolecole codificate geneticamente
Description:
Development of novel technologies for the directed evolution of genetically encoded biomolecules
Keywords:
Biochemical technology, Genetic selection, Genetically modified organisms
ATECO code:
[72.11] - ricerca e sviluppo sperimentale nel campo delle biotecnologie
Bioingegneria di peptidi e proteine terapeutiche
Description:
Bioengineering of therapeutic peptides and proteins
Keywords:
Molecular design, de novo design, Monoclonal antibodies, Molecular markers and recognition
ATECO code:
[72.11] - ricerca e sviluppo sperimentale nel campo delle biotecnologie
Sviluppo di peptidi macrociclici per la medicina di precisione
Description:
Development of macrocyclic peptides for precision medicine
Keywords:
Combinatorial chemistry, Molecular chemistry, Macromolecular chemistry
Computational drug discovery
Other members of the research group:
Leone BACCIU
Achille GIACOMETTI
Matteo GRAZIOSO
Silvia MULTARI
Marco Salvatore NOBILE
Development and characterisation of macrocyclic peptides
SSD:
BIO/10
Development of novel directed evolution methodologies and recombinant surface display technologies
SSD:
BIO/10
Other members of the research group:
Sara LINCIANO
Ottimizzazione sintesi peptidi su fase solida e relative modifiche strutturali
SSD:
CHIM/06
Other members of the research group:
Alessandro SCARSO
Selection and engineering of antibodies and nanobodies
SSD:
BIO/10
Other members of the research group:
Zhanna ROMANYUK
Selection and engineering of genetically encoded peptides and proteins
SSD:
BIO/10
Other members of the research group:
Ylenia MAZZOCATO
Sintesi di derivati peptidici coniugati per medicinal chemistry di precisione
SSD:
CHIM/06
Other members of the research group:
Alessandro SCARSO
Sintesi selettive e sostenibili di peptidi mediante minimizzazione scarti
SSD:
CHIM/06
Other members of the research group:
Alessandro SCARSO
Targeted drug delivery and imaging
SSD:
CHEM-07/A
Other members of the research group:
Francesca BORDIGNON
Sara LINCIANO
A novel integrated cyclic peptide-based platform for precision delivery of nucleic acid-based therapeutics (ALLIANCE)
Funding body:
National Center for Gene Therapy and Drugs based on RNA - Piano Nazionale di Ripresa e Resilienza (PNRR) - Ministero dell'università e della ricerca e Unione Europea (NextGenerationEU)
Type:
Altri programmi ministeriali
Role in the project:
LD
Starting date:
Year: 2024 Length in months: 12
Other members of the research group:
Fabrizio FABRIS
Giulia FIORANI
Cristian FREGONESE
Achille GIACOMETTI
Sara LINCIANO
Sara LINCIANO
Silvia MULTARI
Marco Salvatore NOBILE
Federico POLO
Flavio ROMANO
Zhanna ROMANYUK
Matilde SALVADORETTI
Alessandro SCARSO
Marta SIMEONI
Class IIa HDACs as therapeutic targets in human diseases: new roles and new selective inhibitors
Funding body:
Ministry of Education, University and Research (MIUR)
Type:
PRIN
Role in the project:
PT
Starting date:
Year: 2019 Length in months: 36
Il criceto dorato (Mesocricetus auratus) come modello animale per l’utilizzo di anticorpi monoclonali a scopo terapeutico per le malattie infettive a carattere zoonosico
Funding body:
The Ministry of Health
Type:
Altri programmi ministeriali
Role in the project:
PT
Starting date:
Year: 2020 Length in months: 24
Macrocyclic peptides targeting unexplored class IIa HDAC binding sites: towards the development of novel cancer therapy
Funding body:
Fondazione AIRC per la Ricerca sul Cancro e Commissione Europea (Horizon 2020)
Type:
Altri finanziamenti per progetti di ricerca
Role in the project:
LD
Starting date:
Year: 2020 Length in months: 36
Novel molecular target for diagnosis and therapy in early esophageal cancer
Funding body:
The Ministry of Health
Type:
Altri programmi ministeriali
Role in the project:
PT
Starting date:
Year: 2021 Length in months: 36
Reducing SARS-CoV-2 spread in the human body via the aerosolized delivery of cell-shielding PEGylated bicyclic peptides (RELIEVED)
Funding body:
Ministry of Education, University and Research (MIUR)
Type:
FIRB/FIR/SIR
Role in the project:
LD
Starting date:
Year: 2021 Length in months: 6
Sviluppo di un bioprocesso innovativo e biocompatibile per la produzione sostenibile di nanosistemi di diagnostica molecolare a base peptidica in Veneto
Funding body:
European Social Fund Plus (ESF+) – Veneto Regional Programme 2021/2027
Type:
Altri finanziamenti per progetti di ricerca
Role in the project:
LD
Starting date:
Year: 2023 Length in months: 12
Other members of the research group:
Giulia FIORANI
Achille GIACOMETTI
Federico POLO
Alessandro SCARSO
Targeting class IIa HDACs to reset super-enhancers activity in cancer cells: towards selective epigenetic therapies in the 3D reality
Funding body:
Ministero dell’Univerista’ e della Ricerca (MUR)
Type:
PRIN
Role in the project:
PT
Starting date:
Year: 2024 Length in months: 24