Patents

Patent protection plays a strategic role and offers competitive advantage to companies and entities interested in innovating their process and products.
Ca' Foscari promotes an Industrial Property culture that encourages investment in research and development and, to this end, supports its researchers in patent filing and managing relations with entities and businesses.

PInK offers a technology transfer process that covers the following services:

  • scouting of scientific results
  • search for opportunities of funding and technological enhancement
  • consultancy in the prior state search and filing phases
  • promotion and opportunity for exploitation of inventions, including through participation in technological showcasing or generalist trade fairs, to facilitate the meeting between the demand and the supply of technology innovation.

Registered patents

The patents listed below, in chronological order of filing, are available for licensing or transfer agreements from the dates indicated in each patent.
All Ca' Foscari patents are found in Knowledge Share, the portal that contains the patents filed by the main Italian universities and research institutes.

Inhibitory compounds to fight neurodegeneration and tumors

Monoacylglycerol lipase (MAGL) is an enzyme naturally present in many brain cells and involved in physio-pathological processes (regulation of inflammation, anxiety, immune modulation, motor coordination ...), yet its overexpression/upregulation can cause neuroinflammatory diseases and tumors. Its inhibition has a high therapeutic potential: new reversible inhibitory compounds have been tested, reducing the side effects of the irreversible inhibitors so far studied, and proved to be effective in laboratory on various tumor cell lines (e.g. colorectal, breast and ovarian cancer); they could also treat other MAGL-mediated pathologies (such as multiple/lateral sclerosis, Alzheimer's and Parkinson's disease).

Holders: University of Pisa, Ca’ Foscari University of Venice
Inventors: University of Pisa: Carlotta Granchi, Giulia Bononi, Marco Macchia, Filippo Minutolo, Giulio Poli, Diana Scalabrini, Tiziano Tuccinardi, Antonio Giordano; Ca’ Foscari University of Venice: Flavio Rizzolio
Italian application: 102020000007150
Available for license or transfer agreements from 14/05/2020


From waste to commodity: continuous flow lignin fractionation

Lignin is a polymer that constitutes 30% of the lignocellulosic materials and the residue of agricultural and forestry processes, such as pulp & paper and modern biorefinery processes. Currently disposed via combustion, or applied in low value applications, it can find increasingly innovative destinations of greater industrial interest as a commodity, thanks to methods of fractionation with high reproducibility. The patented system allows the first fractionation of lignin in continuous flow, fully automatable at an industrial scale.

Holders: Ca’ Foscari University of Venice, North Carolina State University
Inventors: Claudia Crestini, Heiko Lange, Dimitris Argyropoulos
USA application: US62/784,030, international application: PCT/EP2019/086784
Available for license or transfer agreements from 17/01/2020


Palladium: less toxic chemotherapy

Targeted, efficient and non-toxic anti-cancer drugs: a new class of palladium compounds could be used as innovative chemotherapeutic molecules against various types of cancers, limiting the typical side effects of treatments with cisplatin or related compounds, in use since the late 1970s. The new compounds have been tested as anti-proliferating agents on some of the most aggressive tumors, such as ovarian, cervical, colon and lung cancers, achieving very promising results. It will be possible to produce highly efficient drugs, in the form of intravenous, intramuscular or subcutaneous solutions, pills or tablets. 

Holder: Ca’ Foscari University of Venice
Inventors: Fabiano Visentin, Thomas Scattolin, Enrica Bortolamiol, Flavio Rizzolio
Italian application: 102019000023079
Available for license or transfer agreements from 19/12/2019


Chemotherapy: Imatinib drug monitoring

The effectiveness of many anticancer drugs varies significantly depending on the drug and the individual patient, for which an incorrect dosage could be useless or even harmful. Therapeutic drug monitoring allows determining the optimal dose to administer, now in a much more expeditious and simple way thanks to the first electrochemical method that determines the concentration of the drug Imatinib in the patient's plasma. The invention can be developed as an on-site test delivering results in real time.

Holders: Ca’ Foscari University of Venice, Centro di Riferimento Oncologico di Aviano
Inventors: Gregorio Bonazza, Salvatore Daniele, Federico Polo, Stefano Tartaggia, Giuseppe Toffoli
Italian application: 102019000008808, international application: PCT/IB2020/055545
Available for license or transfer agreements from 29/08/2019


Chemotherapy: Irinotecan drug monitoring

The effectiveness of many anticancer drugs varies significantly from patient to patient, necessitating customized doses to avoid side effects. The invention applies for the first time an electrochemical method of therapeutic monitoring of the drug Irinotecan. The method enables determining in a rapid and simple manner the drug concentration in the patient's plasma; thus favouring establishment of the optimal dose. The method can be developed in a portable device that performs the test and reads the results in real time.

Holders: Ca’ Foscari University of Venice, Centro di Riferimento Oncologico di Aviano
Inventors: Gregorio Bonazza, Salvatore Daniele, Federico Polo, Stefano Tartaggia, Giuseppe Toffoli
Italian application: 102019000008841, international application: PCT/IB2020/055546
Available for license or transfer agreements from 29/08/2019


Tactile sensor for robotic arm

Sensitive robots... or at least their "skin": among the amazing developments of biorobotics, a new tactile sensor transforms the outermost layer of a robot arm into a sort of artificial skin. The receptor, applied over a relatively large area, is in fact able to perceive intensity and point of application of forces, imitating the human sense of touch. Innovative for lightness and adaptability to curved areas, it can cover large surfaces of robotic prostheses and/or collaborative robotic arms.

Holders: Scuola Superiore Sant’Anna, Pisa; Università degli Studi di Roma "La Sapienza"; Istituto Italiano di Tecnologia, Genova; Università Campus Bio-Medico di Roma; Ca’ Foscari University of Venice
Inventors: Jessica D’Abbraccio, Luca Massari, Calogero Maria Oddo, Eduardo Palermo, Emiliano Schena, Edoardo Sinibaldi, Giuseppe Terruso, Martina Zaltieri
Italian application: 102019000003657
Available for license or transfer agreements from 29/08/2019


A more intuitive way of writing online in Japanese

Japanese written language uses two phonetic alphabets (hiragana and katakana) in addition to sinograms (kanji), not to mention the fact that... it has no spaces between words. This makes it considerably difficult for anyone who wants to learn, write or translate a text in Japanese, becoming even more complicated when the writing has to go through the web. The new method for language teaching, invented by researchers at Ca’ Foscari, is based on Long Unit Words and facilitates the translation process and the learning of the written language by native speaker children and by foreign learners of all ages.

Holder: Ca’ Foscari University of Venice
Inventors: Marcella Maria Mariotti, Alessandro Mantelli
Italian application: 102019000002235
Available for license or transfer agreements from 29/08/2019


Dynamic digestate recirculation for the treatment of organic waste

Two-phase anaerobic digestion systems with digestate recirculation, are now standard in the treatment of organic waste (Organic Fraction of Municipal Solid Waste – OFMSW - or other fermentable organic waste). The patent optimizes the process by automatically managing the ratio of digestate recirculation, applying a mathematical model based on the pH in the fermentation reactor, to control the rate flow.

Holders: Ca' Foscari University of Venice, University of Verona, Sapienza University of Rome
Inventors: David Bolzonella, Cristina Cavinato, Marco Gottardo, Mauro Majone, Federico Micolucci, Paolo Pavan, Francesco Valentino
Italian application: 102018000008006, international application: PCT/IB2019/056702
Available for license or transfer agreements from 10/09/2018


Production of PHAs for bioplastics and biogas from municipal solid waste

Municipal solid waste (OFMSW) can be reused and enhanced in many useful ways: among these is the fermentation of its organic fraction to obtain thermoplastic polyester polymers (PHAs), precursors of bioplastics and biogas. The patented method uses mixed microbial cultures (MMCs) and combines a biological process with a filtering system to optimized the production.

Holders: Sapienza University of Rome, Ca' Foscari University of Venice, University of Verona
Inventors: David Bolzonella, Marco Gottardo, Mauro Majone, Federico Micolucci, Paolo Pavan, Francesco Valentino
Italian patent granted: 102018000003322, international application: WO2019171316
Available for license or transfer agreements from 08/04/2018


Electrochemical sensor for PFAs detection in water

This innovative electrochemical sensor measures in the field, with immediate and inexpensive response, the concentration of Perfluorooctane Sulfonate (PFOS), one of the most widespread and polluting PFAs in groundwater. The sensor is based on a Molecularly Imprinted Polymer (MIP sensor) made ad hoc. Read more

Holder: Ca' Foscari University of Venice
InventorsPaolo UgoNajmeh KarimianAngela Maria StortiniLigia Maria Moretto
Italian patent granted: 102017000026417
Available for license or transfer agreements from 12/06/2017


Bismuth silicates for better luminescence

A very simple synthesis procedure can create luminescent compounds that exploit the non-linear optical properties of bismuth silicates. The characteristics of lower cost and toxicity combined with greater flexibility of use make it a compound suitable for use in biomedical and therapeutic fields, in lighting as well as in anti-counterfeiting.

Holder: Ca' Foscari University of Venice
Inventors: Michele Back, Pietro Riello
Italian patent granted: 102015000025007
Available for license or transfer agreements from 12/06/2017


Remote measurement of waves for safety and research in the seas

Cameras synchronized, not in contact with water and carried on any type of body in motion (e.g. a boat or an off-shore platform) can collect and analyse images of the sea surface and reconstruct the wave spectrum in 4D (space + time). High precision, accuracy and simplicity of calibration make it a method of great interest for commercial navigation, safety at sea and scientific research.

Holders: Ca' Foscari University of Venice, National Research Council
Inventors: Francesco Barbariol, Alvise Benetazzo, Filippo Bergamasco, Sandro Carniel, Mauro Sclavo, Andrea Torsello
Italian patent granted:
102015000082942
Available for license or transfer agreements from 12/06/2017


Patents towards the market

Green cosmetics

An innovative process for producing a high-end cosmetic base, not only consisting of components derived naturally or produced from waste, but also capable of active ingredients controlled release, thus guaranteeing their optimal penetration into the skin for maximized effectiveness. The process allows the formulation of a final product reducing to a minimum the number of ingredients and raw materials, eliminating the use of some components (such as surfactants), which are generally essential in this type of preparation.

The formulation, invented by Michela Signoretto, Federica Menegazzo, Elena Ghedini and registered with the Italian patent no. 102018000005118 and international application: WO2019215592, has been granted for exclusive license use to VeNice, the Ca' Foscari spin-off specialised in innovative, effective, 100% sustainable natural cosmetics.


Photovoltaic cells: clean energy from wine waste

Giving value to waste as a precious renewable resource: for the first time, agri-food waste can be exploited to create photovoltaic cells that produce sustainable electricity. From the residues derived from winemaking (normally disposed of without any other use), researchers can extract natural dyes that capture solar energy, transforming them into a regenerated green resource.

The working group led by Professor Elisa Moretti and including Manuel Meneghetti, Stefano Meneghetti, Enrico Rodrigues Castellon, Aldo Talon, Emilio Celotti, after preliminary studies under an ESF [DHI1] [FS2] project financed by the Veneto Region, carried out research and experiments together with Serena Wines 1881, which resulted in the filing of a patent (Italian application: 102019000006939) in co-ownership. The company then acquired the Ca’ Foscari quota and signed an agreement to develop a prototype and possibly scale up the invention.


A look at the future through new... lenses

Using a method devised by researchers Elti Cattaruzza, Omar Grasso and Marco Mardegan, glass lenses for sunglasses can be given a wide range of colours in a simpler, safer way easily integrated with existing production lines.
Before this invention, state of the art in surface colouring of the glass was the widespread Hydrogen Firing method (thermal treatment of glass in the presence of hydrogen gas). The prototype developed in the Ca’ Fascari laboratories instead dyes the glass lenses by immersing them in a molten salt bath of a suitable composition: the colour can thus be varied thanks to the exchanges of chemical species between the salt and the glass, without the use of hydrogen , which is a flammable and explosive gas. It can also be implemented simultaneously with the chemical tempering (hardening) of the glass to increase its impact resistance.

The patent, Italian application no. 102016000043786, was sold to Luxottica Group, a leading company in the design, production and distribution of high-end, luxury and sports eyewear present throughout the world with a global wholesale network that reaches more than 150 countries in five continents.


Therapeutic Zirconia: development of new nanoparticles against cancer

Zirconia-based materials have long been used in medicine, for example in prostheses, but with no possible application in diagnosis and treatment. Researchers Alvise Benedetti, Pietro Riello and Gabriele Sponchia have synthesized new totally mesoporous zirconium oxide nanoparticles using an innovative sol-gel type technique that enables a high degree of control of the shape and diameter of the nanoparticles and of the porosity of the compound. These nanoparticles, due to their capacity for incorporation into the cells of different biological systems are non-toxic and can be applied in the biomedical field (diagnosis of cancer and other pathologies, more effective drug delivery than Silica). They can also be applied in sectors such as cosmetics (e.g. as a carrier of active ingredients, antioxidants and emollient agents), in the dental and prosthetic fields and in regenerative medicine (e.g. production of biocompatible scaffolds).

An invention with great potential that has raised the interest of Brenta srl: this innovative startup of Ninetreesgroup S.p.A. that deals with nanotech for the chemical-pharmaceutical industry, decided to invest in this discovery by purchasing the patent (Italian application no. 0001428445, international application: WO2016120795).


Call to collaborations: inventions and technologies

Green reagent preparation: organic carbonates

Organic carbonates are non-toxic compounds that are highly biodegradable, excellent substitutes for harmful solvents and additives in the production of pharmaceuticals, fuels and lubricants. The production process of the compound, until now highly toxic, takes advantage of a new procedure that is faster, more environmentally friendly and enables large-scale application of the product.

Inventors: Maurizio Selva (Ca' Foscari University of Venice), Fabrizio Cavani, Tommaso Tabanelli (Alma Mater Studiorum - University of Bologna)