Biosensors for precision nanomedicine

Research group 

Federico Polo, Associate Professor

Collaborations

Dr. Silvio Quici, ISTM, National Research Council
Dr. Fabio Rizzo, ISTM, National Research Council
Prof. Lidia Armelao, University of Padua 
Prof. Francesco Paolucci, University of Bologna
Dr. Giovanni Valenti, University of Bologna
Prof. Ilaria Palchetti, University of Firenze
Dr. Aline S. C. Fabricio, CRIBT, ULSS 12 Veneziana
Dr. Massimo Gion, CRIBT, ULSS 12 Veneziana
Prof. Matteo Mauro, Université de Strasbourg
Prof. Neso Sojic, Université de Bordeaux
Dr. Cristian A. Strassert, CeNTech, Germany
Dr. Vivek Pachauri,Universität Aachen, Germany
Prof. Laura Fabris, Rutgers University, NJ, USA
Prof. J.François Masson, Université Montréal, Canada
Prof. Ivan Guryanov, St. Petersburg S. University, Russia

Research topics

Electron Transfer and Electrogenerated Chemiluminescence

The study of electron transfer (eT) mechanism in (bio-)molecular systems is of paramount importance to decipher structure-related properties to develop new technologies, whose applications range from catalysis and sustainable energy production to biosensing platforms. Electrogenerated chemiluminescence (ECL) is a fascinating phenomenon caused by highly exergonic eT reaction between electrogenerated radicals leading to the formation of an excited state species that emits a photon. ECL finds applications in biosensors and light-emitting devices.

Analytical Tools: Biosensing Platforms

Advances of nanotechnology, micro- and nano-fabrication, and integration of electrochemical and optical (SPR, SERS) technologies can provide the building blocks to develop highly selective and sensitive devices and will play a pivotal role in cancer research in the near future. In fact, they can provide the essential tools for fast, quantitative, and inexpensive analyses. Early diagnosis of circulating cancer protein biomarkers and therapeutic drug monitoring (TDM) represent a niche in the field of biosensing in oncology that still lacks integrated technologies and competences, and thus needs to be explored in depth. 

Sustainable Energy Production

Functionalized electrode surfaces and novel nanostructured materials can serve as catalytic site to generate sustainable energy (e.g. “green hydrogen”) or high-performance batteries. A better understanding of the properties of such materials in terms of efficient electron transfer holds a tremendous fallout with respect to climate change and can help implementing existing technologies and developing new ones. New technologies are highly sought to possibly stop global warming and to provide the next generations with the necessary tools to generate/consume sustainable and renewable energy, while taking care of our home planet.

Last update: 25/05/2022